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1. WO2020182947 - MACROCYCLES WITH ANTIOXIDANT AND NEUROPROTECTIVE ACTIVITIES

Publication Number WO/2020/182947
Publication Date 17.09.2020
International Application No. PCT/EP2020/056665
International Filing Date 12.03.2020
IPC
A61K 31/407 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
407condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61P 25/28 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
A61P 39/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
39General protective or antinoxious agents
06Free radical scavengers or antioxidants
CPC
A61K 31/407
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
407condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
A61P 25/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
A61P 39/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
39General protective or antinoxious agents
06Free radical scavengers or antioxidants
Applicants
  • INSTITUTO BIOMAR, S.A [ES]/[ES]
Inventors
  • FERNÁNDEZ MEDARDE, Antonio
  • VINUESA NAVARRO, María de los Ángeles
  • SÁNCHEZ LÓPEZ, José María
  • BOLAÑOS HERNÁNDEZ, Juan Pedro
  • ALMEIDA PARRA, María de los Ángeles
  • FERNÁNDEZ SÁNCHEZ, Emilio
Agents
  • ABG INTELLECTUAL PROPERTY LAW, S.L.
Priority Data
19382179.012.03.2019EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MACROCYCLES WITH ANTIOXIDANT AND NEUROPROTECTIVE ACTIVITIES
(FR) MACROCYCLES PRÉSENTANT DES ACTIVITÉS ANTIOXYDANTES ET NEUROPROTECTRICES
Abstract
(EN)
Compounds of general formula wherein the wavy bond ~ is either a double bond or the epoxide, or pharmaceutically acceptable salts, solvates, tautomers, or stereoisomers thereof, for use in the treatment of diseases associated with oxidative stress.
(FR)
La présente invention concerne des composés de formule générale : (formule) dans laquelle la liaison ondulée ~ représente soit une double liaison soit l'époxyde, ou des sels, des solvates, des tautomères ou des stéréo-isomères pharmaceutiquement acceptables de ceux-ci, destinés à être utilisés dans le traitement de maladies associées au stress oxydatif.
Also published as
Latest bibliographic data on file with the International Bureau