Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020102273 - BISMUTH METAL-ORGANIC FRAMEWORKS FOR USE AS X-RAY COMPUTED TOMOGRAPHY CONTRAST AGENTS

Publication Number WO/2020/102273
Publication Date 22.05.2020
International Application No. PCT/US2019/061069
International Filing Date 13.11.2019
IPC
A61K 31/19 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
A61K 31/277 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
275Nitriles; Isonitriles
277having a ring, e.g. verapamil
A61K 31/352 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
Applicants
  • NORTHWESTERN UNIVERSITY [US]/[US]
  • NANJING TECH UNIVERSITY [CN]/[CN]
Inventors
  • FARHA, Omar K.
  • ZHANG, Lin
  • ROBISON, Lee N.
Agents
  • MANNING, Michelle
  • BELL, Callie M.
  • KALAFUT, Christopher
  • POREMBSKI, N. Meredith
Priority Data
62/760,20113.11.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BISMUTH METAL-ORGANIC FRAMEWORKS FOR USE AS X-RAY COMPUTED TOMOGRAPHY CONTRAST AGENTS
(FR) STRUCTURES ORGANOMÉTALLIQUES À BASE DE BISMUTH DESTINÉES À ÊTRE UTILISÉES EN TANT QU'AGENTS DE CONTRASTE DE TOMODENSITOMÉTRIE À RAYONS X
Abstract
(EN)
Metal-organic frameworks with bismuth cluster nodes (Bi-MOFs) and methods of using the Bi-MOFs as contrast agents in medical imaging systems, such as computerized tomography (CT) systems, are provided. Contrast compositions that include the Bi-MOFs in a carrier in forms suitable for administration to a patient are also provided. The Bi-MOFs include those with Bi6 nodes connected by multitopic organic linkers.
(FR)
L'invention concerne des structures organométalliques comportant des nœuds de grappe de bismuth (Bi-MOF) et des procédés d'utilisation des Bi-MOF en tant qu'agents de contraste dans des systèmes d'imagerie médicale, tels que des systèmes de tomodensitométrie (CT). L'invention concerne également des compositions de contraste qui comprennent les Bi-MOF dans un support sous des formes appropriées permettant une administration à un patient. Les Bi-MOF comprennent des compositions de contraste présentant des nœuds de Bi6 reliés par des lieurs organiques multitopiques.
Latest bibliographic data on file with the International Bureau