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1. WO2020101790 - METHODS OF USING A PHENOXYPROPYLAMINE COMPOUND TO TREAT PAIN

Publication Number WO/2020/101790
Publication Date 22.05.2020
International Application No. PCT/US2019/049492
International Filing Date 04.09.2019
IPC
A61K 31/454 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
445Non-condensed piperidines, e.g. piperocaine
4523containing further heterocyclic ring systems
454containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A61P 25/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 25/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
04Centrally acting analgesics, e.g. opioids
A61P 25/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
02for peripheral neuropathies
A61P 29/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
Applicants
  • MINERVA NEUROSCIENCES, INC. [US]/[US]
Inventors
  • LUTHRINGER, Remy
  • NOEL, Nadine
  • SAOUD, Jay
Agents
  • ERLACHER, Heidi A.
  • ELRIFI, Ivor R.
  • PAXTON, Thomas J.
Priority Data
62/726,80004.09.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS OF USING A PHENOXYPROPYLAMINE COMPOUND TO TREAT PAIN
(FR) PROCÉDÉS D'UTILISATION D'UN COMPOSÉ PHÉNOXYPROPYLAMINE POUR LE TRAITEMENT DE LA DOULEUR
Abstract
(EN)
The present disclosure relates to methods of treating pain, fibromyalgia, neuropathy, chemotherapy-induced pain, promoting an antihyperalgesic effect, and reducing sensitivity to pain, in a subject in need of such treatment comprising the administration of a therapeutically effective amount of Compound I, or a pharmaceutically acceptable salt, solvate, or prodrug thereof.
(FR)
La présente invention concerne des procédés de traitement de la douleur, de la fibromyalgie, de la neuropathie, de la douleur induite par une chimiothérapie, de promotion d'un effet antihyperalgésique, et de réduction de la sensibilité à la douleur, chez un sujet ayant besoin d'un tel traitement, comprenant l'administration d'une quantité thérapeutiquement efficace du composé I, ou d'un sel, solvate ou promédicament pharmaceutiquement acceptable de celui-ci.
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