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1. WO2020033768 - USE OF INHALED NITRIC OXIDE (INO) FOR THE IMPROVEMENT OF SEVERE HYPOXEMIA

Publication Number WO/2020/033768
Publication Date 13.02.2020
International Application No. PCT/US2019/045806
International Filing Date 08.08.2019
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
16
Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
10
Preparation of respiratory gases or vapours
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
02
Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
0205
Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1455
using optical sensors, e.g. spectral photometrical oximeters
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
15
Inhalators
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
16
Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
A61M 16/10 (2006.01)
A61B 5/0205 (2006.01)
A61B 5/145 (2006.01)
A61B 5/1455 (2006.01)
A61M 15/00 (2006.01)
A61M 16/00 (2006.01)
Applicants
  • BELLEROPHON THERAPEUTICS [US/US]; 184 Liberty Corner Road, Suite 302 Warren, NJ 07059, US
Inventors
  • SHAH, Parag; US
  • QUINN, Deborah; US
Agents
  • GRIFFIN, Gail, H.; US
  • CHAI, Deping; US
  • BEARDELL, Louis, W.; US
  • CAO, Ping; US
  • GRIFFIN, Gail, H.; US
Priority Data
62/717,43310.08.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF INHALED NITRIC OXIDE (INO) FOR THE IMPROVEMENT OF SEVERE HYPOXEMIA
(FR) UTILISATION D'OXYDE NITRIQUE INHALÉ (INO) POUR L'AMÉLIORATION DE L'HYPOXÉMIE SÉVÈRE
Abstract
(EN)
Described are methods for improving oxygen saturation in patients suffering from hypoxemia, wherein said patients are receiving a continuous flow of oxygen at 10L/min and exhibit an initial oxygen saturation of at least about 88%, comprising administering inhaled nitric oxide to said patients in an outpatient setting. Methods for improving quality of life for a hospitalized patient, reducing patient hospitalization time, and reducing costs associated with patient hospitalization are also described.
(FR)
L'invention concerne des procédés pour améliorer la saturation en oxygène chez des patients souffrant d'hypoxémie, lesdits patients recevant un flux continu d'oxygène à 10 l/min et présentant une saturation initiale en oxygène d'au moins environ 88 %, ces procédés comprenant l'administration d'oxyde nitrique inhalé aux patients en ambulatoire. L'invention concerne également des procédés permettant d'améliorer la qualité de vie d'un patient hospitalisé, de réduire le temps d'hospitalisation du patient et de réduire les coûts associés à l'hospitalisation du patient.
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